Effect of Inorganic Cations on the Biocidal and Cellular Activity of Glutaraldehyde |
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| Authors: | S. P. GORMAN EILEEN M. SCOTT |
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| Affiliation: | Department of Pharmacy, The Queen's University of Belfast, Medical Biology Centre, Belfast BT9 7BL, Northern Ireland |
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| Abstract: | Increased bactericidal activity was observed on addition of inorganic cations to both acid and alkaline glutaraldehyde solutions. Mg2+ ion in particular potentiated activity and this was attributed to cell surface effects due to osmotic forces resulting in greater uptake of disinfectant, reduction in cell volume and interference with enzyme activity associated with the cell wall. |
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