(1) Department of Medical Microbiology and Immunology, College of Medicine, University of South Florida, Fl 33612, Tampa;(2) Esoteric Testing and Research Department, Clinical Laboratory, Tampa General Hospital, Fl 33606, Davis Islands
Abstract:
Background
Studies examining herpesvirus-herpesvirus (cytomegalovirus (CMV)-Epstein-Barr virus (EBV)) interactions are limited, and many of the studies have been clinical observations suggesting such an interaction exists. This report aims to examine the in vitro susceptibilities of BJAB-B1 and P3HR-1 cells (EBV positive Burkitt's lymphoma B-cell lines) to a CMV superinfection; and show that EBV reactivation occurs after CMV superinfects these cell lines.