Production and secretion of chondroitin sulfates and dermatan sulfate by established mammalian cell lines |
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| Authors: | H Saito B G Uzman |
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| Affiliation: | 1. Department of Pharmacy, Weifang Medical University, Weifang, Shandong, China;2. Department of Pharmacy, Jining Medical University, Rizhao, Shandong, China;3. Rongsense Aquatic Food Group Co. LTD, Rizhao, Shandong, China;1. CREED, University of Amsterdam, Netherlands;2. Tinbergen Institute, Netherlands |
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| Abstract: | Ten established mammalian cell lines of different origin (lymphoid, epithelial and fibroblastic) were found to produce and secrete a mixture of chondroitin sulfates A, C and dermatan sulfate into the medium. The rates of production and secretion of the total sulfated mucopolysaccharides as well as the proportion of individual mucopolysaccharides differ strikingly among different cell lines. |
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