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The migration of paraxial and lateral plate mesoderm cells emerging from the late primitive streak is controlled by different Wnt signals |
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| Authors: | Dylan Sweetman Laura Wagstaff Oliver Cooper Cornelis Weijer Andrea Münsterberg |
| Institution: | (1) School of Biological Sciences, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, UK;(2) Biomedical Research Centre, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, UK;(3) Centre for Neuroregeneration Research, Harvard Medical School, McLean Hospital, 02478 Belmont, MA, USA;(4) College of Life Sciences Biocentre, MSI/WTB complex, University of Dundee, Dow Street, DD1 5EH Dundee, UK |
| Abstract: | BackgroundCo-ordinated cell movement is a fundamental feature of developing embryos. Massive cell movements occur during vertebrate gastrulation and during the subsequent extension of the embryonic body axis. These are controlled by cell-cell signalling and a number of pathways have been implicated. Here we use long-term video microscopy in chicken embryos to visualize the migration routes and movement behaviour of mesoderm progenitor cells as they emerge from the primitive streak (PS) between HH stages 7 and 10. |
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