Structural studies of the O-antigenic polysaccharide of Escherichia coli O86, which possesses blood-group B activity |
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| Authors: | M Andersson N Carlin K Leontein U Lindquist K Slettengren |
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| Affiliation: | Department of Vaccine Development and Production, National Bacteriological Laboratory, Stockholm, Sweden. |
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| Abstract: | The O-specific side-chains of the lipopolysaccharide from Escherichia coli O86:K2:H2 have been investigated using n.m.r. spectroscopy, methylation analysis, and specific degradations, and shown to be composed of the pentasaccharide repeating-unit (formula; see text) which represents the biological repeating-unit. The blood-group B activity was confirmed by an enzyme-linked immunosorbent assay. |
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