Sodium periodate stimulation of human lymphocytes : A comparison between normal and chronic lymphocytic leukemia lymphocytes |
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Authors: | T. M. Monahan R. R. Fritz C. W. Abell |
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Affiliation: | 1. Department of Radiology, Albert Einstein College of Medicine, Bronx, N.Y. 10461, USA;2. Department of Microbiology, College of Physicians and Surgeons, New York, N.Y. 10032, USA |
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Abstract: | Lymphocytes from healthy donors and from patients with chronic lymphocytic leukemia (CLL) were stimulated to divide with sodium periodate. The time of maximal response of normal lymphocytes to sodium periodate (NaIO4) was earlier than that observed to phytohemagglutinin (PHA), but the magnitude was lower. In comparison, CLL lymphocytes responded to NaIO4 more extensively and earlier than to PHA. |
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Keywords: | Author to whom reprint requests should be addressed. |
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