Synthesis of type 2 Adenovirus DNA in the Presence of Cycloheximide |
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Authors: | Marshall S Horwitz Carol Brayton and Stephen G Baum |
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Institution: | 1Departments of Microbiology and Immunology, Pediatrics, Cell Biology, and Medicine, Albert Einstein College of Medicine, Bronx, New York 10461 |
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Abstract: | Adenovirus type 2 DNA synthesis, either in permissive human cells or nonpermissive monkey cells, becomes independent of protein synthesis after the appearance of progeny viral DNA. In the presence of cycloheximide, semiconservative replication and initiation of progeny molecules can occur. |
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