The role of stress in rheumatic diseases |
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Authors: | Afton L Hassett Daniel J Clauw |
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Affiliation: | (1) Chronic Pain & Fatigue Research Center, Department of Anesthesiology, University of Michigan Medical School, 24 Frank Lloyd Wright Drive, Lobby M, PO Box 385, Ann Arbor, Michigan 48106, USA |
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Abstract: | Rheumatology patients frequently note the occurrence of stressful or traumatic life events prior to the onset of their illness and/or a relationship between stress and disease flares. For our patients, identifying causal events could represent an effort to give meaning to a chronic and often disabling disease, while noting a link between stress and flares may proffer a sense of control. Whatever purpose the report of stress as an etiological or maintaining factor may serve, the science exploring a causal relationship between stress and autoimmune disease onset and course is expanding. Moreover, stress can also induce symptoms such as pain via nonimmunological mechanisms. |
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