Kinetic resolution for optically active epoxides by microbial enantioselective hydrolysis |
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| Authors: | Won Jae Choi Eun Chul Huh Hyoung Jun Park Eun Yeol Lee Cha Yong Choi |
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| Institution: | (1) Department of Chemical Technology, College of Engineering, Seoul National University, Seoul, Korea;(2) Interdisciplinary Program for Biochemical Engineering and Biotechnology, College of Engineering, Seoul National University, Seoul, Korea;(3) Samsung Chemical Group, 11TH FI., Samsung Life Bldg., Taepyrungro 2 ga, Chung-ku, Seoul, Korea |
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| Abstract: | Resolution of several racemic epoxides was accomplished using an epoxide hydrolase activity of whole cells of the newly isolated Aspergillus niger. (S)-Styrene oxide, for example, was obtained from its racemates with optical purity of 100% ee and 32% yield. © Rapid Science Ltd. 1998 |
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