Salmonella typhimurium forms adenylcobamide and 2-methyladenylcobamide, but no detectable cobalamin during strictly anaerobic growth |
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| Authors: | B Keck P Renz |
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| Institution: | Institut für Biologische Chemie und Ern?hrungswissenschaft, Universit?t Hohenheim, Garbenstrasse 30, D-70599 Stuttgart, Germany e-mail: b-c-nutr@uni-hohenheim.de, Tel.: +49-711-4592284, Fax: +49-711-4592283, DE
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| Abstract: | Under microaerophilic conditions Salmonella typhimurium LT2 synthesizes cobalamin, during which 5,6-dimethylbenzimidazole is formed from riboflavin. We report here that in an anoxic
environment S. typhimurium did not form cobalamin, but rather adenylcobamide, 2-methyladenylcobamide, and cobyric acid. This indicated that S. typhimurium, like other microorganisms that synthesize 5,6-dimethylbenzimidazole from riboflavin, requires oxygen for the formation of
the cobalamin base.
Received: 29 June 1999 / Accepted: 29 September 1999 |
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| Keywords: | 5 6-Dimethylbenzimidazole Factor A Pseudovitamin B12 Riboflavin Salmonella ?typhimurium Vitamin B12 |
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