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Modulated contact frequencies at gene-rich loci support a statistical helix model for mammalian chromatin organization |
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| Authors: | Franck Court Julie Miro Caroline Braem Marie-Noëlle Lelay-Taha Audrey Brisebarre Florian Atger Thierry Gostan Michaël Weber Guy Cathala Thierry Forné |
| Affiliation: | 1.Institut de Génétique Moléculaire de Montpellier (IGMM), UMR5535 CNRS,Universités Montpellier 1 et Montpellier 2. 1919, Route de Mende,Montpellier Cedex 5,France;2.INSERM U827, Laboratoire de Génétique des Maladies Rares, IURC, 64, avenue du Doyen G Giraud,Montpellier Cedex 5,France |
| Abstract: | BackgroundDespite its critical role for mammalian gene regulation, the basic structural landscape of chromatin in living cells remains largely unknown within chromosomal territories below the megabase scale. |
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