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Restriction endonuclease cleavage map of the DNA of JC virus. |
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| Authors: | J D Martin R J Frisque B L Padgett and D L Walker |
| Abstract: | A physical map of the sites cleaved by the following restriction endonucleases was derived for the DNA of JC virus, a human polyomavirus: EcoRI, HpaI, and PstI (one site each); HindII (four sites); and HindIII (three sites). By agarose gel electrophoresis of fragmented DNA, the size of full-length DNA of JC virus was estimated to be 5,125 +/- 105 base pairs (98 +/- 2% of the length of simian virus 40 DNA). |
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