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Mutagenic effects of short term action of N-methyl-N’-nitro-N-nitrosoguanidine onChlamydomonas geitleri
Authors:J Nečas  Daniela Pavingerová
Institution:(1) Laboratory of Biotechnology, Institute of Microbiology, Czechoslovak Academy of Sciences, Opatovicky mlyn, 379 81 Třeboň, Czechoslovakia
Abstract:A possible method of finding the best concentration of a chemical mutagen or a shortterm action is demonstrated by the results obtained withChlamydomonas geitleri. Mostly two cases occur. We must either use the shortest time of the mutagen action with a sufficiently high effect or utilize the whole limited time for this action using a suitable concentration with a similar effect. It is possible to choose such a structure of the doae of the chemical mutagen which in the mutation spectrum ensures either the optimal frequencies of all components or of only some of them chosen beforehand.
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