壳聚糖-g-N.羧甲基-二(2-苯并眯唑)-1,2-乙二醇的制备及其性能

以2-溴乙酸、壳聚糖、二（2-苯并咪唑）-1，2-乙二醇为原料，利用接枝作用将化学修饰后的小分子药物二（2-苯并咪唑）-1，2-乙二醇连接在天然高分子壳聚糖（CTS）上。并以。HNMR，IR，热分析及XRD等方法对其结构进行表征并研究接枝聚合物的理化性质。本文采用络合滴定法测定了接枝聚合物对一系列重金属离子的吸附作用；采用震荡法进行悬菌定量杀菌实验；还以经典的静态失重法研究了合成的聚合物在腐蚀介质中对N80钢片腐蚀的抑制作用。结果表明：小分子药物-（2-苯并咪唑）-1，2-乙二醇在接枝到天然高分子壳聚糖后热稳定性提高，在酸中具有良好的溶解度，对金属离子吸附能力在一个较宽温度范围内得以保持；同时增强了抑菌力，降低了最小抑菌浓度；利用BBIE与CTS韵协同作用提高了聚合物对金属腐蚀的抑制能力。

Preparation of Chitosan-g-N-carboxymethyl-bi (2-benzoimidazole)-1,2-ethandiol Reagent and Its Characters

Small molecule reagent named bi(2-benzoimidazole)-1 ,2-ethandiol chemicaly modified links with natural pol-ymer-chitosan by grafting polymerization with 2-bromoacetic acid as raw material. Its structure and physical, chemical characters have been measured by ~1H NMR,IR,XRD and thermal analysis. Adsorption tests of grafting polymers for metal ions such as:Cd~(2+),CrO_4~(2-),Fe~(3+),Cu~(2+),Pb~(2+) on grafling polymer have been determined with EDTA complex titration; The antibacterial activity of grafting polymer has been examined against a series of test microorganism by quantitative suspension method; corrosion inhibition efficiency of synthesized polymers in certain erosion medium for N80 steel panel has been measured by weight-loss method. Results from experiments indicate that small molecule compound' s thermal stability is strengthened with its grafting with natural polymer-chitosan and grafting polymerization adds to its solubility in acid system. Its adsorption for metal ions could be retained at certain level within a wide temperature range and its antibacterial efficacy is enhanced, decreasing minimal inhibition criteria ( MIC). Inhibition of polymer to metal erosion can be retained according to coordination of BBIE and CIS.