cmdABCDEF, a cluster of genes encoding membrane proteins for differentiation and antibiotic production in Streptomyces coelicolor A3(2) |
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Authors: | Pengfei Xie Ana Zeng Zhongjun Qin |
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Institution: | (1) Key Laboratory of Synthetic Biology, Shanghai Institute of Plant Physiology and Ecology, Shanghai, PR China |
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Abstract: | Background
Streptomyces coelicolor is the most studied Streptomyces species and an excellent model for studying differentiation and antibiotic production. To date, many genes have been identified
to be required for its differentiation (e.g. bld genes for aerial growth and whi genes for sporulation) and antibiotics production (including actII-orf4, redD, cdaR as pathway-specific regulatory genes and afsR, absA1/A2 as pleiotropic regulatory genes). |
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Keywords: | |
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