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Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland
Affiliation:1. Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki 00014, Finland;2. Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA;3. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA;4. Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, 02142, USA;5. National Institute of Health and Welfare, Helsinki 00271, Finland;6. Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA;7. Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA;8. Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA;9. Department of Public Health, University of Helsinki, Helsinki 00014, Finland;10. Helsinki Institute for Information Technology and Department of Mathematics and Statistics, University of Helsinki, Helsinki 00014, Finland
Abstract:
Keywords:genetic prediction  population stratification  genetic structure
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