SPLICE, a computer program for automated extraction of information from GenBank sequence entries

SPLICE, a software tool for the extraction of sequences fromfiles in GenBank tape format, has been developed. The programcan analyze the features table in this format and use any ofthe information provided to write the corresponding sequencesinto a standard sequence file format suitable for use with sequenceanalysis programs. Sequences that are present as several subsequentfragments in a single GenBank file, such as those encoding apeptide, can be spliced together by the program. Further, sequencesthat are present in more than one Genbank file, such as an exonwhich spans several different files, can also be spliced intoone sequence. SPLICE runs under the MS/DOS and Unix operatingsystems, can be called as a sub-process by other programs andcan process batches of files. Received on December 26, 1989; accepted on May 30, 1990