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Incidence of inherited enzyme activity variants in feral mouse populations
Authors:Grahame Bulfield  Jean M Hall  Spyros Tsakas
Institution:(1) Department of Genetics, University of Leicester, LE1 7RH Leicester, UK;(2) Department of Genetics, Agricultural College of Athens, Votanicos, Athens, Greece;(3) Present address: Genetics Group, ARC Poultry Research Centre, EH25 9PS Roslin, Midlothian, UK;(4) Present address: Department of Biochemistry, Medical School, University of Nottingham, Nottingham, UK
Abstract:We have screened 173 wild caught mice (Mus musculus) from multiple sites in Europe for variation in the activity of 14 enzymes and found 8 different mutants with low enzyme activity; an incidence of 3.69/1000. This compares with the incidence of 3.26/1000 found for low enzyme activity variants in man (Mohrenweiser, 1981).This work was supported by an MRC project grant to G.B.
Keywords:incidence  inherited  enzyme activity variants  feral mice
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