|
|||||
|
|
A novel estrogen receptor ligand template |
|
| Authors: | Sibley Robert Hatoum-Mokdad Holia Schoenleber Robert Musza Laszlo Stirtan William Marrero Diana Carley William Xiao Hong Dumas Jacques |
| Institution: | Bayer Research Center, Bayer Corporation, Pharmaceutical Division, 400 Morgan Lane, West Haven, CT 06516, USA. robert.sibley.b@bayer.com |
| Abstract: | Three synthetic routes towards a novel estrogen receptor ligand template based on a rigid bicyclo-3.3.1]-nonene core have been investigated. The prototype compound exhibits potent binding at the ERbeta receptor and promising estrogen receptor subtype selectivity. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |