| Insect immune resistance to parasitoids |
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| 摘 要： |
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| 关 键 词： | 细胞毒素 血细胞 免疫力 黑素生成 拟寄生物 |
| 收稿时间： | 2007-03-02 |
Insect immune resistance to parasitoids |
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| Authors: | Yves Carton Marylène Poirié Anthony J Nappi |
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| Institution: | Laboratoire Evolution, Génomes et Spéciation, CNRS, 91198 Gif/Yvette, France, and UniversitéParis-Sud 11, 91405 Orsay Cedex, France;UnitéMixte de Recherches 1112 "Réponse des Organismes aux Stress Environnementaux", UniversitéNice-Sophia Antipolis-Institut National de la Recherche Agronomique, 400 route des Chappes, 06903 Sophia-Antipolis, France;Department of Biology, Loyola University of Chicago, Chicago, Illinois, 60525, USA |
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| Abstract: | Insect host-parasitoid interactions involve complex physiological, biochemical and genetic interactions. Against endoparasitoids, immune-competent hosts initiate a blood cell-mediated response that quickly destroys the intruders and envelops them in a multilayered melanotic capsule. During the past decade, considerable progress has been made in identifying some of the critical components of the host response, mainly because of the use of efficient molecular tools. This review examines some of the components of the innate immune response of Drosophila, an insect that has served as an exceptionally good experimental model for studying non-self recognition processes and immune cell signaling mechanisms. Topics considered in this review include hematopoiesis, proliferation and adhesion of hemocytes, melanogenesis and associated cytotoxic molecules, and the genetic aspects of the host-parasitoid interaction. |
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| Keywords: | cytotoxic molecules hemocyte innate immunity melanogenesis parasitoid resistance genes |
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