Cloning of a Putative Neuronal Nicotinic Acetylcholine Receptor Subunit |
| |
| Authors: | Keith E. Isenberg Grant E. Meyer |
| |
| Affiliation: | Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110. |
| |
| Abstract: | A cDNA clone was isolated from a rat superior cervical ganglion cDNA library with an oligonucleotide that hybridized to muscle-like nicotinic acetylcholine receptor (nAChR) subunit cDNA. The deduced amino acid sequence possesses characteristics expected of a nAChR subunit that does not bind acetylcholine, in addition to distinctive features such as unique cysteine residues and N-linked glycosylation sites. |
| |
| Keywords: | Neuronal nicotinic acetylcholine receptor subunit Rat superior cervical ganglion cDNA cloning Sequence homology. |
|
