A MONTE CARLO SIMULATION OF CLONE GROWTH |
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Authors: | Joseph G. Szekely Gregory G. Kennedy Joseph G. Hoffman |
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Affiliation: | Medical Biophysics Branch, Atomic Energy of Canada Limited, Whiteshell Nuclear Research Establishment, Pinawa, Manitoba, and Department of Physics, State University of New York at Buffalo, Buffalo, New York |
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Abstract: | A Monte Carlo simulation of clone growth is discussed from the point of view of clonal volume. It is shown that clone volume is a good representation of the number of cells per clone for a wide range of single cell growth equations. However, the rate at which the coefficient of variation in clonal volume approaches that of cell number per clone is strongly dependent upon the particular growth equation. |
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