Purinoceptors in blood feeding behaviour in the stable fly, Stomoxys calcitrans |
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| Authors: | ANN ASCOLI-CHRISTENSEN JAMES F SUTCLIFFE† PAUL J ALBERT‡ |
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| Institution: | *Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona, U.S.A.;?Department of Biology, Trent University, Peterborough, Ontario, Canada;?Department of Biological Sciences, Concordia University, Montreal, Quebec, Canada |
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| Abstract: | Abstract Both sexes of the stable fly, Stomoxys calcitrans L. (Diptera: Muscidae), have receptors on their mouthparts that mediate blood feeding. The potency ranking of the adenine nucleotides (ATP > ADP > AMP > adenosine) in eliciting feeding and suppressing the NaCl-sensitive cell may indicate the involvement of a P2-type receptor. This is supported by the lack of effect on feeding by methyl xanthines. Feeding-related behavioural and electrophysiological results demonstrate that the potency of CH3-S-ATP is not greater than that of ATP. These ATP-mediated responses are antagonized by ANAPP3. Results support the conclusion that the putative 'ATP receptor' involved in stable fly phagostimulation resembles the P2x purinoceptor of vertebrates. |
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| Keywords: | Stable fly Stomoxys calcitrans blood-feeding electro-physiology purinoception |
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