HLA gene and haplotype frequencies in galicia (NW Spain) |
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| Authors: | T A Varela R Lodeiro J Fariña |
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| Institution: | 1. Dept. de Biología Animal (Antropologia), Fac. de Biologia, Univ. de Santiago. Santiago de Compostela, Espa?a
2. Dept. de Biología Fundamental, Area de Genética, Fac. de Ciencias, Univ. de Vigo. Orense, Campus de Orense, Espa?a
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| Abstract: | The genetic structure of six populations of Iran (Turks, Kurds, Lurs, Zabolis, Baluchis and Zoroastrians) was examined using
data on blood groups, serum proteins and cell enzymes. Our results show conclusively that there are genetic differences among
the six populations and the analysis of superimposed R and S matrices defined by Harpending & Jenkins (1973) show that the
dispersion of some of the alleles correspond to the dispersion of the populations. The FST estimates are not large enough to favour selection on any of the loci studied. The FIT and FIS estimates are positive and moderately high suggesting that the genetic differentiation to some extent is influenced by inbreeding. |
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| Keywords: | HLA antigens Gene frequencies Haplotype frequencies Galicia/Spain |
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