| 黄芫花及桐油提取物对Ⅱ型单纯疱疹病毒诱癌的促进作用 |
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| 引用本文： | 孙瑜,陈敏诲,肖红,刘汉燕,陈晓,曾毅,伊藤洋平.黄芫花及桐油提取物对Ⅱ型单纯疱疹病毒诱癌的促进作用[J].病毒学报,1987(2). |
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| 作者姓名： | 孙瑜 陈敏诲 肖红 刘汉燕 陈晓 曾毅 伊藤洋平 |
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| 作者单位： | 湖北医学院病毒研究所，湖北医学院病毒研究所，湖北医学院病毒研究所，湖北医学院病毒研究所，湖北医学院病毒研究所，中国预防医学科学院病毒学研究所，日本京都大学医学院微生物系 武汉，武汉，武汉，武汉，武汉，北京 |
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| 摘 要： | 本文报道,瑞香科植物黄芫花Wikstroemia chamaedaphne(WC)提取物,及大戟科桐油提取物12-O-hexadecanoyl-16-hydroxyphorboI-13-acetate(HHPA),能促使Ⅱ型单纯疱疹病毒(HSV-2)333株诱发小鼠宫颈癌,其癌发率分别为21.1％和26.3％,而对照组的癌发率仅为7.4％,统计学处理(累积法及权重法计算后,用方差分析),其差异均有显著性,证明WC和HHPA是促癌物。
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| 关 键 词： | Ⅱ型单纯疱疹病毒 黄芫花 桐油提取物 实验性宫颈癌 |
TUMOR PROMOTING EFFECT OF DITERPENE ESTER HHPA AND EXTRACT OF WIKS TROEMIA CHAMAEDAPHNE ON HSV-2 INDUCED CARCINOMA IN MICE |
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| Sun Yu Chen Minhui Xiao Hong Liu Hanyan Chen Xiao Zeng Yi Ito Y Institute of Virology,Hubei Medical College,WuhanInstitute of Virology,Chinese Academy of Preventive Medicine,Beijing.TUMOR PROMOTING EFFECT OF DITERPENE ESTER HHPA AND EXTRACT OF WIKS TROEMIA CHAMAEDAPHNE ON HSV-2 INDUCED CARCINOMA IN MICE[J].Chinese Journal of Virology,1987(2). |
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| Authors: | Sun Yu Chen Minhui Xiao Hong Liu Hanyan Chen Xiao Zeng Yi Ito Y Institute of Virology Hubei Medical College WuhanInstitute of Virology Chinese Academy of Preventive Medicine Beijing |
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| Institution: | Sun Yu Chen Minhui Xiao Hong Liu Hanyan Chen Xiao Zeng Yi Ito Y Institute of Virology,Hubei Medical College,WuhanInstitute of Virology,Chinese Academy of Preventive Medicine,BeijingDepartment of Microbiology,Faculty of Medicine,Kyoto University,Kyoto Japan |
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| Abstract: | The tumor promoting effect of Wistroei chamaedaphne ( WC ) and di-terpene ester 12-0-hexadecanoyl-hydroxyphorbol-13-acetate ( HHPA ) on cervical cancer induced by HSV-2 (333) was studied in hybrid mice. The ratio of cancer induced by WC extract and HHPA with HSV-2 was 21.15 and 26.3%, respectively, the incidence of cancer in the control group ( HSV-2 alone ) was only 7.4%. These data indicate that WC extract and HHPA are tumor promoters which can enhance the development of HSV-2 induced cervical carcinoma in mice. |
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| Keywords: | Herpes Simplex Type 2 W ikstroemia chamae daphne (WC) Tung oil extract ( HHPA ) Induced cervical cancer |
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