Photonics of human saliva: potential optical methods for the screening of abnormal health conditions and infections |
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| Authors: | Jijo Lukose Sanoop Pavithran M. Mithun N. Ajaya Kumar Barik Keerthilatha M. Pai V. K. Unnikrishnan Sajan D. George V. B. Kartha Santhosh Chidangil |
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| Affiliation: | 1.Centre of Excellence for Biophotonics, Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India ;2.Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India ;3.Centre for Applied Nanoscience, Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India |
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| Abstract: | Human saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-invasive and reliable clinical specimen for use in medical diagnostics. This brief review aims to highlight the optical technologies, mainly surface plasmon resonance (SPR), Raman, and Fourier transform infrared (FTIR) spectroscopy, which are being used for the probing of saliva for diverse biomedical applications. Advances in bio photonics offer the promise of unambiguous, objective and fast detection of abnormal health conditions and viral infections (such as COVID-19) from the analysis of saliva. |
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| Keywords: | Photonics Saliva COVID-19 SPR Raman spectroscopy SERS FTIR HPLC-LIF |
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