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Mid-trimester abortion with 15 (S) methyl prostaglandin F
Authors:Theodore Leibman  Luis Saldana  Harold Schulman  Mary Ann Cunningham  Georgia Randolph
Affiliation:Department Gynecology/Obstetrics The Albert Einstein College of Medicine and The Bronx Municipal Hospital Center Bronx, New York USA
Abstract:A Prostaglandin analog 15 Methyl PG F administered intra-muscularly was used to induce mid-trimester abortion in 16 patients. The average dose given was 789 ± 60 ugm, and this resulted in only 9 successful abortions. The incidence of side effects was thought to be prohibitive. PG appears to produce two types of action on the myometrium, a membrane effect, and a more fundamental intracellular regulatory effect.
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