Synthesis of the A,B-ring-truncated OSW saponin analogs and their antitumor activities |
| |
| Authors: | Peng Wenjie Tang Pingping Hu Xiaoyi Liu Jun O Yu Biao |
| |
| Affiliation: | State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China. |
| |
| Abstract: | The A,B-ring-truncated OSW saponin analogs (1, 18a, and 18b) were synthesized. These greatly simplified trans-hydrindane disaccharides retained considerable inhibitory activity against the growth of HeLa and Jurkat T cells (IC(50)=0.8-21.1 microM). |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
