Aggregation of human lymphoblastoid cells by tumor-promoting phorbol esters and dihydroteleocidin B |
| |
Authors: | H Hoshino M Miwa H Fujiki T Sugimura |
| |
Institution: | National Cancer Center Research Institute, Tsukiji, Chuo-ku, Tokyo 104 Japan |
| |
Abstract: | Human lymphoblastoid cells transformed by Epstein-Barr virus aggregated rapidly in the presence of tumor-promoting phorbol esters and dihydroteleocidin B. Cell aggregation was almost complete after incubation for 6 hours. In amounts of a few ng, they induced significant aggregation. Their abilities to aggregate cells could be measured quantitatively and correlated well with their effects in promoting skin tumors. |
| |
Keywords: | EB Epstein-Barr ODC ornithine decarboxylase PBS PDD phorbol-12 13-didecanoate 4α-PDD 4α-phorbol-12 13-didecanoate TPA |
本文献已被 ScienceDirect PubMed 等数据库收录! |