Assignment of human prochymosin pseudogene to chromosome 1 |
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| Authors: | M Kolmer T Ord L Alhonen J M Hyttinen M Saarma R Villems J J?nne |
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| Affiliation: | Department of Biochemistry and Biotechnology, University of Kuopio, Finland. |
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| Abstract: | Chymosin is an extremely specific aspartatic protease responsible for milk coagulation. Chymosin is expressed in a number of mammalian offspring, yet its presence in the gastric tissue of human infants remains a matter of controversy. In any event, the human genome contains chymosin-related sequences that probably represent a pseudogene. Using DNA obtained from human x hamster somatic cell hybrids as the template and polymerase chain reaction, we have mapped the human prochymosin pseudogene to chromosome 1. |
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