Chemical analysis and biological activities of the essential oil of Teucrium leucocladum Boiss. (Lamiaceae) |
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| Affiliation: | 1. Faculty of Pharmacy, Department of Pharmacognosy, Zagazig University, Zagazig, Egypt;2. Faculty of Science, Department of Zoology, Zagazig University, Zagazig, Egypt;1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China;2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China;1. Agriculture Ministry Key Laboratory of Healthy Freshwater Aquaculture & Key Laboratory of Freshwater Aquatic Animal Genetic and Breeding of Zhejiang Province, Zhejiang Institute of Freshwater Fisheries, Huzhou 313001, China;2. Key Laboratory of Freshwater Fishery Germplasm Resources, Shanghai Ocean University, Ministry of Agriculture, Shanghai 201306, China |
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| Abstract: | The chemical composition of the water-distilled essential oil and n-hexane–ether extract of Teucrium leucocladum Boiss. were determined by GLC and GLC–MS. Altogether 72 compounds were identified. The sesquiterpene alcohols, patchouli alcohol (31.24% and 29.66%) and α-cadinol (9.29% and 21.54%) were the main components in the oil and the extract, respectively. α-Cadinol was isolated and characterized using MS, 1H- and 13C-NMR spectral analyses. Furthermore, the oil and the extract were tested for their bacterostatic and antifungal activities; they showed broad and potent activity against Pseudomonas aeruginosa, Bacillus subtilis and Candida albicans. A marked larvicidal activity of the essential oil, n-hexane–ether extract and crude ethanolic extract was also observed against Culex pipiens, Musca domestica and Ceratitis capitata larvae. |
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