| 骨形成蛋白15基因的研究进展 |
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| 引用本文： | 侯振平,蒋思文.骨形成蛋白15基因的研究进展[J].遗传,2003,25(6):725-728. |
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| 作者姓名： | 侯振平 蒋思文 |
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| 作者单位： | 华中农业大学农业部猪遗传育种重点开放实验室，武汉 430070
Agricultural Ministry Key Laboratory of Pig Genetics and Breeding,Huazhong Agricultural University,Wuhan 430070,China |
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| 基金项目： | 湖北省自然科学基金(2002AB099)，留学回国基金资助 |
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| 摘 要： | 骨形成蛋白是属于转移生长因子-β超家族生长因子的一种分泌型信号分子。迄今为止，已有30多个骨形成蛋白被确定，骨形成蛋白15基因在卵母细胞中表达，具有推动卵泡生长，阻止黄体早熟的作用。本文综述了骨形成蛋白15基因的研究现状。
Abstract:Bone morphogenetic proteins (BMPs) are secreted signalling molecules belonging to the transforming growth factor-β (TGF-β) surperfamily.Up to date,more than 30 members of BMPs are identified.Bone morphogenetic protein-15 is only expressed in oocytes.Oocyte-specific BMP-15 might promote follicle growth in vivo,while preventing premature luteinization.This paper biefly discusses the progress in the research area of BMP-15 gene being as a candidate gene for litter size.
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| 关 键 词： | 骨形成蛋白 转移生长因子-β bone morphogenetic proteins transforming growth factor-β 骨形成蛋白15基因 Key words |
| 文章编号： | 0253-9772(2003)06-0725-04 |
| 修稿时间： | 2002年10月8日 |
Advance in Bone Morphogenetic Protein-15 Gene |
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| Zhen-Ping Hou,Si-Wen Jiang.Advance in Bone Morphogenetic Protein-15 Gene[J].Hereditas,2003,25(6):725-728. |
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| Authors: | Zhen-Ping Hou Si-Wen Jiang |
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| Institution: | Agricultural Ministry Key Laboratory of Pig Genetics and Breeding, Huazhong Agricultural University, Wuhan 430070, China. |
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| Abstract: | Bone morphogenetic proteins (BMPs) are secreted signalling molecules belonging to the transforming growth factor-beta (TGF-beta) surperfamily. Up to date,more than 30 members of BMPs are identified. Bone morphogenetic protein-15 is only expressed in oocytes. Oocyte-specific BMP-15 might promote follicle growth in vivo, while preventing premature luteinization. This paper briefly discusses the progress in the research area of BMP-15 gene being as a candidate gene for litter size. |
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