An unanswered 2003 letter appealing on behalf of all mankind to Nobel Laureate Roderick McKinnon to use his newfound fame and visibility to begin restoring honesty and integrity to basic biomedical science by rebutting or correcting suspected plagiarism in his Nobel-Prize-winning work

The centerpiece of this document is an unanswered letter of appeal from the author to Professor Roderick MacKinnon of the Rockefeller University dated November 17, 2003. The aim of the appeal is summarized in the title of this communication. In addition to the 2003 letter, there are also two follow-up letters in this communication, each containing a copy of the 2003 letter and each repeating the appeal. The follow-up letters, dated February 22, 2008 and April 2, 2008 respectively, were also unanswered. To make sure that these letters reached their destination, each was certified with delivery time and date affirmed. Thus the February 22 letter was delivered on the February 24 by the US Postal Service. Two copies of the April 2 follow-up letter were sent. The first copy was delivered by Federal Express on April 4. The second copy of the April 2 letter was delivered by the US Postal Service on the same day. Thus all told three additional copies of the 2003 letters were delivered to, and must be in the hand of Professor MacKinnnon. All these efforts were made to make certain that Professor MacKinnon's refusal to answer my registered 2003 letter was not due to his not having received a copy of that letter.