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Aurora kinase inhibitor restrains STAT5-activated leukemic cell proliferation by inducing mitochondrial impairment
Authors:Jin-Xing Wang  Ling Zhang  Ze-Wei Huang  Xue-Ning Zhang  Yan-Yan Jiang  Fang-Jie Liu  Liang Long  Man-Jie Xue  Gui Lu  Quentin Liu  Zi-Jie Long
Affiliation:1. Department of Hematology, The Third Affiliated Hospital, Institute of Hematology, Sun Yat-sen University, Guangzhou, China;2. Department of Hematology, The Third Affiliated Hospital, Institute of Hematology, Sun Yat-sen University, Guangzhou, China

Jin-Xing Wang and Ling Zhang contributed equally to this study.;3. Department of Hematology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China;4. Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China;5. Medical Research Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

Abstract:
Keywords:AML  AURKA inhibitor  mitochondrial impairment  STAT5  targeted therapy
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