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PTPN21-CDSlong isoform inhibits the response of acute lymphoblastic leukemia cells to NK-mediated lysis via the KIR/HLA-I axis
Authors:Huafang Wang  Ni Zhu  Xiaohang Ye  Limengmeng Wang  Binsheng Wang  Wei Shan  Xiaoyu Lai  Yamin Tan  Shan Fu  Haowen Xiao  He Huang
Institution:1. Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang, China

Zhejiang Engineering Laboratory for Stem cell and Immunotherapy, Hangzhou, Zhejiang, China;2. Department of Hematology, The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China;3. Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China;4. Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang, China;5. Department of Hematology, The Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

Abstract:
Keywords:acute lymphoblastic leukemia  human leukocyte antigens class I molecules  isoform  NK killing  protein tyrosine phosphatase non-receptor type 21
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