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Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes,but does not reduce the inhibitory effects of enzalutamide
Authors:Ethan P. Metz  Phillip J. Wilder  Jixin Dong  Kaustubh Datta  Angie Rizzino
Affiliation:1. Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska;2. Department of Biochemistry and Molecular Biology, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska
Abstract:
Keywords:enzalutamide  neuroendocrine  notch signaling  prostate tumor cells  PSA  SOX2
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