| 肝脏注射醋酸引起局部坏死的实验研究 |
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| 引用本文： | 邹晓平 牛燕陵. 肝脏注射醋酸引起局部坏死的实验研究[J]. 上海生物医学工程, 1999, 20(2): 46-48 |
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| 作者姓名： | 邹晓平 牛燕陵 |
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| 作者单位： | 第二军医大学长海医院消化内科，第二军医大学长海医院消化内科，第二军医大学长海医院消化内科，第二军医大学长海医院消化内科，第二军医大学长海医院消化内科 上海 200433，上海 200433，上海 200433，上海 200433，上海 200433 |
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| 摘 要： | 本实验的目的是证实醋酸可引起肝局部坏死，并且作用强于无水乙醇。对鼠肝局部注射醋酸后，从大体及组织学改变观察局部坏死情况并寻找最适浓度。结果发现醋酸可引起注射局部坏死完全，与周围分界非常清晰，其中５０％醋酸引起的坏死区平均直径最大，且明显优于无水乙醇。提示醋酸可以作为一种制剂，用于局部注射治疗肝癌。
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| 关 键 词： | 醋酸 肝坏死 肝癌 治疗 |
THE EXPERIMENT STUDY OF INTERHEPATIC INJECTION OF ACETIC ACID RESULTING IN LOCAL NECROSIS |
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| Zou XiaoPing Niu YianLin YiNin XuGuoMing Jin ZenDong Dept of Gastroenterology,Changhai Hospital,the Second Military Medical University. THE EXPERIMENT STUDY OF INTERHEPATIC INJECTION OF ACETIC ACID RESULTING IN LOCAL NECROSIS[J]. Shanghai Journal of Biomedical Engineering, 1999, 20(2): 46-48 |
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| Authors: | Zou XiaoPing Niu YianLin YiNin XuGuoMing Jin ZenDong Dept of Gastroenterology Changhai Hospital the Second Military Medical University |
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| Abstract: | Objective:To confirm acetic acid injection can cause local necrosis of liver and its effect beyond absolute ethanol. Methods: after percutaneous acetic acid injection, the effect of coagulation necrosis in the liver of rats was detected by pathology. Results: necrosis occurred around the injection site of difference concentration of acetic acid into the liver. The mean diameter of the nerotic area caused by 50% acetic and is the largest and statistically significantly larger than that caused by absolute ethanol. Conclusion:Acetic acid may be proved to be an effective material for treating small hepatocellular carcinoma |
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| Keywords: | Acetic acid Absolute ethanol Hepatic local necrosis |
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