Isolation and characterization of AStreptomyces C5 mutant strain hyperproductive of extracellular protease

Summary A pleiotropic streptomycete mutant was isolated that overproduced extracellular protease activity on azocasein, whereas the parent strain,Streptomyces C5, produced only negligible extracellular azocaseinase activity. Also unlike the parent strain, the mutant, designated C5-A13, was nonpigmented, and was unable to sporulate or produce antibiotics.