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Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis
Authors:Pauline D Scanlan  Fergus Shanahan  Julian R Marchesi
Affiliation:(1) Alimentary Pharmabiotic Centre, National University of Irel, University College Cork, Cork, Ireland;(2) Department of Microbiology, National University of Ireland, University College Cork, Cork, Ireland;(3) Department of Medicine, National University of Ireland, University College Cork, Cork, Ireland;(4) Division of Microbiology, School of Biosciences, Cardiff University, Park Place, CF10 3US Cardiff, Wales, UK
Abstract:

Background  

The incidence and diversity of human methanogens are insufficiently characterised in the gastrointestinal tract of both health and disease. A PCR and clone library methodology targeting the mcrA gene was adopted to facilitate the two-fold aim of surveying the relative incidence of methanogens in health and disease groups and also to provide an overview of methanogen diversity in the human gastrointestinal tract.
Keywords:
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