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Epibatidine isomers and analogues: structure-activity relationships |
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| Authors: | White Richard Malpass John R Handa Sandeep Richard Baker S Broad Lisa M Folly Liz Mogg Adrian |
| Institution: | Department of Chemistry, University of Leicester, Leicester LE1 7RH, UK. |
| Abstract: | Binding affinities for a range of epibatidine isomers and analogues at the alpha4beta2 and alpha3beta4 nAChR subtypes are reported; compounds having similar N-N distances to epibatidine show similar, high potencies. |
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