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An Exact Confidence Interval for the Ratio of Two Related Proportions
Authors:R A Parker
Abstract:I propose an exact confidence interval for the ratio of two proportions when the proportions are not independent. One application is to estimate the population prevalence using a screening test with perfect specificity but imperfect sensitivity. The population prevalence is the ratio of the observed prevalence divided by the test's sensitivity. I describe a method to calculate exact confidence intervals for this problem and compare these results with approximate confidence intervals given previously.
Keywords:Cystic fibrosis  Genetic screening  Population prevalence  Relative risk  Sensitivity  Specificity
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