Production of enterotoxin,verotoxin, hemolysin and cytotoxic necrotizing factor byEscherichia coli of intestinal and extraintestinal origin |
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Authors: | A Ho?tacká |
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Institution: | (1) Research Institute of Preventive and Clinical Medicine, 833 01, Bratislava |
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Abstract: | Seventy-sixEscherichia coli strains were examined for heat-labile enterotoxin (LT), verotoxin (VT), hemolysin (HLy) and cytotoxic necrotizing factor
(CNF). Thirty-six strains were isolated from patients suffering from diarrhea and forty from different extraintestinal infections.
The number of LT-producing strains was low (2.6%) (one of intestinal and one of extraintestinal origin). Verotoxin was produced
only by one extraintestinal strain. Four intestinal strains were hemolytic (11.2%) and also positive for CNF. From 24 hemolytic
strains of extraintestinal origin (60%), 17 produced also CNF. Most of the hemolytic (30%) as well as CNF-producing strains
(22.5%) were isolated from urine. Our results are similar to those of other studies confirming the close association between
hemolysin and CNF production as well as a possible role of these toxic factors in pathogenesis of extraintestinal, infections
caused byE. coli. |
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Keywords: | |
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