A CALCIUM ACTIVATED PROTEASE IN SQUID AXOPLASM |
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| Authors: | Harish C PANT Susumu Terakawa Harold Gainer |
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| Institution: | Laboratory of Neurobiology, NIMH;Laboratory of Developmental Neurobiology, N1CHD, NIH, Bethesda, MD 20014, U.S.A. and The Marine Biological Laboratory, Woods Hole, MA 02543, U.S.A. |
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| Abstract: | Evidence for a protease in squid axoplasm which is selectively activated by Ca2+ and blocked by SH-inhibitors is presented. This protease appears to be particularly effective in degrading squid neurofilament proteins, but also extensively degrades various other major protein components in axoplasm. |
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