Effect of arthropod extracts on the multiplication of Toxoplasma gondii in mouse peritoneal macrophages |
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Authors: | Chinchilla Carmona Misael Herrera Corrales Marlen Guerrero Bermúdez Olga Marta Jiménez Somarribas Alberto Tamayo Guiselle Sittenfeld Appel Ana Nielsen Vanessa Hurtado Priscila |
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Affiliation: | Centro de Investigación en Enfermedades Tropicales, Departamento de Parasitología, Facultad de Microbiología, Universidad de Costa Rica, 2060, Costa Rica. |
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Abstract: | Treatment of toxoplasmosis usually causes secondary effects. It is important to find active substances extracted from natural organisms. In this work we studied some arthropod extracts that have effect against Toxoplasma multiplication inside mouse macrophages. After studying 382 extracts, 23 were selected on the basis of the activity and we found that 13 extracts from orders Polydesmida, Lepidoptera, Orthoptera and Hymenoptera exerted an important inhibition of Toxoplasma multiplication. |
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