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Sarbecovirus ORF6 proteins hamper induction of interferon signaling
Authors:Izumi Kimura  Yoriyuki Konno  Keiya Uriu  Kristina Hopfensperger  Daniel Sauter  So Nakagawa  Kei Sato
Affiliation:1. Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo 1088639, Japan;2. Graduate School of Medicine, The University of Tokyo, Tokyo 1130033, Japan;3. Institute of Molecular Virology, Ulm University Medical Center, Ulm 89081, Germany;4. Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen 72076, Germany;5. Department of Molecular Life Science, Tokai University School of Medicine, Kanagawa 2591193, Japan;6. CREST, Japan Science and Technology Agency, Saitama 3220012, Japan
Abstract:
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  • Keywords:SARS-CoV-2  COVID-19  ORF6  type I interferon  type III interferon  interferon-stimulated gene
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