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Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis
Authors:Irene Anastasia  Nicolò Ilacqua  Andrea Raimondi  Philippe Lemieux  Rana Ghandehari-Alavijeh  Guilhem Faure  Sergei L. Mekhedov  Kevin J. Williams  Federico Caicci  Giorgio Valle  Marta Giacomello  Ariel D. Quiroga  Richard Lehner  Michael J. Miksis  Katalin Toth  Thomas Q. de Aguiar Vallim  Eugene V. Koonin  Luca Scorrano  Luca Pellegrini
Affiliation:1. Graduate Program in Neuroscience, Faculty of Medicine, Laval University, Quebec, QC, Canada;2. Mitochondria Biology Laboratory, Brain Research Center, Quebec, QC, Canada;3. Experimental Imaging Center, San Raffaele Scientific Institute, Milan, Italy;4. Broad Institute of MIT and Harvard, Cambridge, MA, USA;5. National Center for Biotechnology Information, NLM, NIH, Bethesda, MD, USA;6. Department of Biological Chemistry, Geffen School of Medicine, UCLA, Los Angeles, CA, USA;7. Department of Biology, University of Padua, Padua, Italy;8. Instituto de Fisiología Experimental, CONICET, UNR, Rosario, Argentina;9. Department of Pediatrics, University of Alberta, Edmonton, AB, Canada;10. Department of Engineering Science and Applied Mathematics, Northwestern University, Evanston, IL, USA;11. Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada;12. Department of Medicine, Division of Cardiology, UCLA, Los Angeles, CA, USA;13. Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Quebec, QC, Canada
Abstract:
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  • Keywords:mitochondria  endoplasmic reticulum  wrappER  inter-organelle contact  lipoprotein  VLDL  Rrbp1  MUP  MAM  liver metabolism
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