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Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
Authors:Haidong Huang  Xingjiang Yu  Xiangzi Han  Jing Hao  Jianjun Zhao  Gurkan Bebek  Shideng Bao  Richard A Prayson  Ahmad M Khalil  Eckhard Jankowsky  Jennifer S Yu
Institution:1. Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, NE60, Cleveland, OH 44195, USA;2. Department of Nutrition, Center for Proteomics and Bioinformatics, Case Western Reserve University, 10900 Euclid Avenue, BRB 921, Cleveland, OH 44106, USA;3. Department of Anatomic Pathology, The Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA;4. Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA;5. Center for RNA Science and Therapeutics, Case Western Reserve University, 10900 Euclid Avenue, Wood Bldg. 137, Cleveland, OH 44106, USA;6. Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, 9500 Euclid Avenue, CA50, Cleveland, OH 44195, USA
Abstract:
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  • Keywords:glioma stem cell  glioblastoma  Piwi  piRNA  BTG2  FBXW7  cell cycle  apoptosis  senescence  CT antigen
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