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Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity
Authors:Xian Zhou  Xingxing Zhu  Chaofan Li  Yanfeng Li  Zhenqing Ye  Virginia Smith Shapiro  John A. Copland  Taro Hitosugi  David A. Bernlohr  Jie Sun  Hu Zeng
Affiliation:1. Division of Rheumatology, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA;2. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA;3. Department of Biostatistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA;4. Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA;5. Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA;6. Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA;7. Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
Abstract:
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  • Keywords:B cell  stearoyl-CoA desaturase  monounsaturated fatty acid  mTOR  autophagy  humoral immunity
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