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Optic nerve regeneration screen identifies multiple genes restricting adult neural repair
Authors:Jane A Lindborg  Nicholas M Tran  Devon M Chenette  Kristin DeLuca  Yram Foli  Ramakrishnan Kannan  Yuichi Sekine  Xingxing Wang  Marius Wollan  In-Jung Kim  Joshua R Sanes  Stephen M Strittmatter
Institution:1. Cellular Neuroscience, Neurodegeneration, Repair, Departments of Neurology and of Neuroscience, Yale University School of Medicine, New Haven, CT 06536, USA;2. Center for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA;3. Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06536, USA
Abstract:
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  • Keywords:optic nerve  axon regeneration  IL-22  AAV  CRISPR  shRNA  gene editing  retina  inflammation
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