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Overcoming Expressional Drop-outs in Lineage Reconstruction from Single-Cell RNA-Sequencing Data
Authors:Tianshi Lu  Seongoh Park  James Zhu  Yunguan Wang  Xiaowei Zhan  Xinlei Wang  Li Wang  Hao Zhu  Tao Wang
Institution:1. Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;2. Department of Statistics, Sungshin Women’s University, Seoul 02844, Republic of Korea;3. Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;4. Department of Statistical Science, Southern Methodist University, Dallas, TX 75275, USA;5. Department of Mathematics and Department of Computer Science and Engineering, University of Texas at Arlington, Arlington, TX 76019, USA;6. Children’s Research Institute, Department of Pediatrics and Department of Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Abstract:
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  • Keywords:scRNA-seq  lineage tracing  drop-out  genetics
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